Introduction of Cystic Fibrosis

Original paragraph:   

Cystic fibrosis (CF) is a genetic disorder that particularly affects the lungs and digestive system.

CF affects more than 30,000 kids and young adults in the United States. It disrupts the normal function of epithelial cells — cells that make up the sweat glands in the skin and that also line passageways inside the lungs, liver, pancreas, and digestive and reproductive systems.

The inherited CF gene directs the body's epithelial cells to produce a defective form of a protein called CFTR (or cystic fibrosis transmembrane conductance regulator) found in cells that line the lungs, digestive tract, sweat glands, and genitourinary system.

When the CFTR protein is defective, epithelial cells can't regulate the way that chloride (part of the salt called sodium chloride) passes across cell membranes. This disrupts the essential balance of salt and water needed to maintain a normal thin coating of fluid and mucus inside the lungs, pancreas, and passageways in other organs. The mucus becomes thick, sticky, and hard to move.

Normally, mucus in the lungs traps germs, which are then cleared out of the lungs. But in CF, the thick, sticky mucus and the germs it has trapped remain in the lungs, which become infected.

 Key ideas:

•  Cystic Fibrosis is a genetic disorder.
• It disrupts the normal function of epithelial cells.
• Inherited CF gene produce a defective form of protein called CFTR (Cystic Fibrosis Conductance Regulator)
• When CFTR is defective,epithelial cells can't regulate sodium chloride. 
• Problems towards the balance of salt and water needed.
• Mucus become thick,sticky and hard to move.
• Mucus that is trapped in certain organ which may become infected.

 The picture shows differences between a normal airway and an airway with cystic fibrosis as well as the affect to various organs.

http://www.nhlbi.nih.gov/health/health-topics/images/cysticfibrosis01.jpg

Source in MLA:

"Cystic Fibrosis." KidsHealth - the Web's Most Visited Site about Children's Health. Ed. Floyd R. Livingston Jr. The Nemours Foundation, 01 Apr. 2014. Web. 06 Oct. 2014. <http://kidshealth.org/parent/medical/digestive/cf.html>.

Paraphrasing:

In general , Cystic Fibrosis is an inherited disease nor genetic disorder that is caused by a faulty gene which disturbs the usual function of epithelial cells. Epithelial cells are cells that builds up the sweat glands in skin and lines passageways in various systems . Normally , the inherited Cystic Fibrosis gives instructions to the body to produce a certain protein called CFTR(cystic fibrosis transmembrane conductance regulator) which creates sweat , saliva , tears , mucus and enzymes. However, if there are complications in the CFTR, these cells may not control the amount of sodium chloride giving troubles to the balance between salt and water reducing its ability to produce thin coating fluid and mucus. Apart from that ,with the thick, sticky mucus covering parts such as the lungs, liver, pancreas, and digestive system , it has provided a much more less functional organs and systems.

More about Cystic Fibrosis:

Videos mainly explains more about cystic fibrosis in detail and how the inherited disease impact individuals.
https://www.youtube.com/watch?v=FMAOEOmLoUE
https://www.youtube.com/watch?v=WuI72eMrIQI&list=PLJBkk17XfXmlRZAGbEqflDw_8tIsuE7RS